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CHMP1B anticorps (AA 1-199)

CHMP1B Reactivité: Humain IHC, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7147518
  • Antigène Voir toutes CHMP1B Anticorps
    CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
    Épitope
    • 15
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-199
    Reactivité
    • 24
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 23
    • 1
    Lapin
    Clonalité
    • 24
    Polyclonal
    Conjugué
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CHMP1B est non-conjugé
    Application
    • 23
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Charged multivesicular body protein 1b protein (1-199AA)
    Isotype
    IgG
    Top Product
    Discover our top product CHMP1B Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))
    Autre désignation
    CHMP1B (CHMP1B Produits)
    Synonymes
    anticorps C10orf2, anticorps C18-ORF2, anticorps C18orf2, anticorps CHMP1.5, anticorps Vps46-2, anticorps Vps46B, anticorps hVps46-2, anticorps 2810405I11Rik, anticorps Chmp1b1, anticorps Chmp1.5, anticorps fb10c03, anticorps wu:fb10c03, anticorps zgc:56134, anticorps chromatin modifying protein 1b, anticorps hypothetical protein, anticorps charged multivesicular body protein 1B, anticorps chromatin modifying protein 1B, anticorps LOC692931, anticorps PGTG_18215, anticorps CHMP1B, anticorps Chmp1b, anticorps chmp1b
    Sujet

    Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B and SPAST to the midbody of dividing cells. Involved in HIV-1 p6- and p9-dependent virus release.

    Aliases: CHMP1B antibody, C18orf2Charged multivesicular body protein 1b antibody, CHMP1.5 antibody, Chromatin-modifying protein 1b antibody, CHMP1b antibody, Vacuolar protein sorting-associated protein 46-2 antibody, Vps46-2 antibody, hVps46-2 antibody

    UniProt
    Q7LBR1
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