CHMP5 anticorps (AA 1-219)

N° du produit ABIN7147529

Détail du produit anti-CHMP5 anticorps

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Épitope: AA 1-219

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHMP5 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Charged multivesicular body protein 5 protein (1-219AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:500-1:1000, IF:1:100-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHMP5

Antigène: CHMP5 (Charged Multivesicular Body Protein 5 (CHMP5))

Autre désignation: CHMP5 (CHMP5 Produits)

Synonymes: anticorps SNF7DC2, anticorps cgi-34, anticorps hspc177, anticorps pnas-2, anticorps vps60, anticorps chmp5, anticorps zgc:64125, anticorps C9orf83, anticorps HSPC177, anticorps PNAS-2, anticorps Vps60, anticorps 2210412K09Rik, anticorps AW545668, anticorps RGD1305968, anticorps charged multivesicular body protein 5 S homeolog, anticorps charged multivesicular body protein 5b, anticorps charged multivesicular body protein 5, anticorps charged multivesicular body protein 5 L homeolog, anticorps chromatin modifying protein 5, anticorps chmp5.S, anticorps chmp5b, anticorps CHMP5, anticorps chmp5.L, anticorps chmp5, anticorps Chmp5

Sujet:

Background: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in HIV-1 p6- and p9-dependent virus release.

Aliases: apoptosis-related protein PNAS-2 antibody, C9orf83 antibody, CGI 34 antibody, Charged multivesicular body protein 5 antibody, CHMP 5 antibody, CHMP family, member 5 antibody, chmp5 antibody, CHMP5_HUMAN antibody, Chromatin modifying protein 5 antibody, Chromatin-modifying protein 5 antibody, Chromosome 9 open reading frame 83 antibody, HGNC:26942 antibody, HSPC177 antibody, hVps60 antibody, PNAS 2 antibody, SNF7 domain containing protein 2 antibody, SNF7 domain-containing protein 2 antibody, SNF7DC2 antibody, Vacuolar protein sorting 60 antibody, Vacuolar protein sorting-associated protein 60 antibody, Vps60 antibody

UniProt: Q9NZZ3