CMKLR1 anticorps (AA 321-373) (Biotin)

N° du produit ABIN7147550

Détail du produit anti-CMKLR1 anticorps (Biotin)

Antigène: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Épitope: AA 321-373

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CMKLR1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Chemokine-like receptor 1 protein (321-373AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CMKLR1

Antigène: CMKLR1 (Chemokine-Like Receptor 1 (CMKLR1))

Autre désignation: CMKLR1 (CMKLR1 Produits)

Synonymes: anticorps CHEMERINR, anticorps ChemR23, anticorps DEZ, anticorps RVER1, anticorps Gpcr27, anticorps mcmklr1, anticorps si:ch211-240b21.3, anticorps CMLKR1, anticorps Cmklr-1, anticorps GPCR, anticorps chemerin chemokine-like receptor 1, anticorps chemokine-like receptor 1, anticorps CMKLR1, anticorps Cmklr1, anticorps cmklr1

Sujet:

Background: Receptor for the chemoattractant adipokine chemerin/RARRES2 and for the omega-3 fatty acid derived molecule resolvin E1. Interaction with RARRES2 induces activation of intracellular signaling molecules, such as SKY, MAPK1/3 (ERK1/2), MAPK14/P38MAPK and PI3K leading to multifunctional effects, like, reduction of immune responses, enhancing of adipogenesis and angionesis. Resolvin E1 down-regulates cytokine production in macrophages by reducing the activation of MAPK1/3 (ERK1/2) and NF-kappa-B. Positively regulates adipogenesis and adipocyte metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2).

Aliases: CHEMERINR antibody, Chemokine like receptor 1 antibody, Chemokine-like receptor 1 antibody, CHEMR23 antibody, CMKLR1 antibody, CML1_HUMAN antibody, DEZ antibody, G protein coupled receptor ChemR23 antibody, G protein coupled receptor DEZ antibody, G-protein coupled receptor ChemR23 antibody, G-protein coupled receptor DEZ antibody, Orphan G protein coupled receptor antibody, Orphan G protein coupled receptor Dez antibody, Resolvin E1 receptor antibody, RVER1 antibody

UniProt: Q99788