CH25H anticorps (AA 142-272)

N° du produit ABIN7147600

Détail du produit anti-CH25H anticorps

Antigène: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Épitope: AA 142-272

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CH25H est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cholesterol 25-hydroxylase protein (142-272AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CH25H

Antigène: CH25H (Cholesterol 25-Hydroxylase (CH25H))

Autre désignation: CH25H (CH25H Produits)

Synonymes: anticorps CH25H, anticorps zgc:101688, anticorps MGC143045, anticorps C25H, anticorps AI462618, anticorps m25OH, anticorps cholesterol 25-hydroxylase, anticorps cholesterol 25-hydroxylase L homeolog, anticorps CH25H, anticorps ch25h, anticorps Ch25h, anticorps ch25h.L

Sujet:

Background: Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation.

Aliases: CH25H antibody, Cholesterol 25-hydroxylase antibody, EC 1.14.99.38 antibody, Cholesterol 25-monooxygenase antibody, h25OH antibody

UniProt: O95992