CHD1 anticorps (AA 1501-1710)

N° du produit ABIN7147714

Détail du produit anti-CHD1 anticorps

Antigène: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Épitope: AA 1501-1710

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CHD1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Chromatin Immunoprecipitation (ChIP)

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Chromodomain-helicase-DNA-binding protein 1 protein (1501-1710AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CHD1

Antigène: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Autre désignation: CHD1 (CHD1 Produits)

Synonymes: anticorps CHD-1, anticorps 4930525N21Rik, anticorps AI851787, anticorps AW555109, anticorps CHD1, anticorps CG3733, anticorps DmCHD1, anticorps Dmel\\CG3733, anticorps chd1, anticorps dCHD1, anticorps l(2)23Cd, anticorps CHD1W, anticorps chromodomain helicase DNA binding protein 1, anticorps Chromodomain-helicase-DNA-binding protein, anticorps Chromodomain-helicase-DNA-binding protein 1, anticorps CHD1, anticorps Chd1, anticorps CHDB1

Sujet:

Background: ATP-dependent chromatin-remodeling factor which functions as substrate recognition component of the transcription regulatory histone acetylation (HAT) complex SAGA. Regulates polymerase II transcription. Also required for efficient transcription by RNA polymerase I, and more specifically the polymerase I transcription termination step. Regulates negatively DNA replication. Not only involved in transcription-related chromatin-remodeling, but also required to maintain a specific chromatin configuration across the genome. Is also associated with histone deacetylase (HDAC) activity (By similarity). Required for the bridging of SNF2, the FACT complex, the PAF complex as well as the U2 snRNP complex to H3K4me3. Functions to modulate the efficiency of pre-mRNA splicing in part through physical bridging of spliceosomal components to H3K4me3. Required for maintaining open chromatin and pluripotency in embryonic stem cells.

Aliases: ATP dependent helicase CHD 1 antibody, ATP-dependent helicase CHD1 antibody, CHD 1 antibody, CHD-1 antibody, Chd1 antibody, CHD1_HUMAN antibody, Chromodomain helicase DNA binding protein 1 antibody, Chromodomain-helicase-DNA-binding protein 1 antibody, DKFZp686E2337 antibody, OTTHUMP00000222625 antibody

UniProt: O14646

Pathways: Chromatin Binding