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BHLHE41 anticorps (AA 185-285)

BHLHE41 Reactivité: Humain WB, ELISA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7147841
  • Antigène Voir toutes BHLHE41 Anticorps
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    Épitope
    • 7
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 185-285
    Reactivité
    • 40
    • 22
    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 31
    • 8
    • 1
    Lapin
    Clonalité
    • 33
    • 7
    Polyclonal
    Conjugué
    • 24
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BHLHE41 est non-conjugé
    Application
    • 29
    • 19
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    Western Blotting (WB), ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)
    Isotype
    IgG
    Top Product
    Discover our top product BHLHE41 Anticorps primaire
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
    Autre désignation
    BHLHE41 (BHLHE41 Produits)
    Synonymes
    anticorps BHLHB3, anticorps dec2, anticorps bhlhb3, anticorps sharp1, anticorps sharp-1, anticorps MGC108143, anticorps DEC2, anticorps SHARP1, anticorps hDEC2, anticorps 6430520M22Rik, anticorps Bhlhb2l, anticorps Bhlhb3, anticorps Sharp1, anticorps Dec2, anticorps SHARP-1, anticorps basic helix-loop-helix family member e41, anticorps basic helix-loop-helix family, member e41, anticorps BHLHE41, anticorps bhlhe41, anticorps Bhlhe41
    Sujet

    Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5\\\'-CACGTG-3\\\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.

    Aliases: Basic helix-loop-helix domain containing class B3 antibody, BHE41_HUMAN antibody, bHLH protein DEC2 antibody, bHLHB3 antibody, bHLHe41 antibody, Class B basic helix loop helix protein 3 antibody, Class B basic helix-loop-helix protein 3 antibody, Class E basic helix-loop-helix protein 41 antibody, DEC2 antibody, Differentially expressed in chondrocytes protein 2 antibody, Enhancer of split and hairy related protein 1 antibody, Enhancer-of-split and hairy-related protein 1 antibody, hDEC2 antibody, Moderately similar to basic-helix loop helix protein M.musculus antibody, SHARP-1 antibody

    UniProt
    Q9C0J9
    Pathways
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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