BHLHE41 anticorps (AA 185-285)
-
- Antigène Voir toutes BHLHE41 Anticorps
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
-
Épitope
- AA 185-285
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp BHLHE41 est non-conjugé
-
Application
- Western Blotting (WB), ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Class E basic helix-loop-helix protein 41 protein (185-285AA)
- Isotype
- IgG
- Top Product
- Discover our top product BHLHE41 Anticorps primaire
-
-
- Indications d'application
- Recommended dilution: WB:1:500-1:5000,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
-
Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Antigène
- BHLHE41 (Basic Helix-Loop-Helix Family, Member E41 (BHLHE41))
- Autre désignation
- BHLHE41 (BHLHE41 Produits)
- Synonymes
- anticorps BHLHB3, anticorps dec2, anticorps bhlhb3, anticorps sharp1, anticorps sharp-1, anticorps MGC108143, anticorps DEC2, anticorps SHARP1, anticorps hDEC2, anticorps 6430520M22Rik, anticorps Bhlhb2l, anticorps Bhlhb3, anticorps Sharp1, anticorps Dec2, anticorps SHARP-1, anticorps basic helix-loop-helix family member e41, anticorps basic helix-loop-helix family, member e41, anticorps BHLHE41, anticorps bhlhe41, anticorps Bhlhe41
- Sujet
-
Background: Transcriptional repressor involved in the regulation of the circadian rhythm by negatively regulating the activity of the clock genes and clock-controlled genes. Acts as the negative limb of a novel autoregulatory feedback loop (DEC loop) which differs from the one formed by the PER and CRY transcriptional repressors (PER/CRY loop). Both these loops are interlocked as it represses the expression of PER1 and in turn is repressed by PER1/2 and CRY1/2. Represses the activity of the circadian transcriptional activator: CLOCK-ARNTL/BMAL1 heterodimer by competing for the binding to E-box elements (5\\\'-CACGTG-3\\\') found within the promoters of its target genes. Negatively regulates its own expression and the expression of DBP and BHLHE41/DEC2. Acts as a corepressor of RXR and the RXR-LXR heterodimers and represses the ligand-induced RXRA/B/G, NR1H3/LXRA, NR1H4 and VDR transactivation activity.
Aliases: Basic helix-loop-helix domain containing class B3 antibody, BHE41_HUMAN antibody, bHLH protein DEC2 antibody, bHLHB3 antibody, bHLHe41 antibody, Class B basic helix loop helix protein 3 antibody, Class B basic helix-loop-helix protein 3 antibody, Class E basic helix-loop-helix protein 41 antibody, DEC2 antibody, Differentially expressed in chondrocytes protein 2 antibody, Enhancer of split and hairy related protein 1 antibody, Enhancer-of-split and hairy-related protein 1 antibody, hDEC2 antibody, Moderately similar to basic-helix loop helix protein M.musculus antibody, SHARP-1 antibody
- UniProt
- Q9C0J9
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
-