COPB1 anticorps (AA 2-200)

N° du produit ABIN7148009

Détail du produit anti-COPB1 anticorps

Antigène: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Épitope: AA 2-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human Coatomer subunit beta protein (2-200AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur COPB1

Antigène: COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))

Autre désignation: COPB1 (COPB1 Produits)

Synonymes: anticorps id:ibd5034, anticorps wu:fc66c05, anticorps zgc:92482, anticorps COPB1, anticorps DKFZp459K154, anticorps COPB, anticorps 2610019B04Rik, anticorps Rack2, anticorps Beta-COP, anticorps coatomer protein complex, subunit beta 1, anticorps coatomer protein complex subunit beta 1 L homeolog, anticorps coatomer protein complex subunit beta 1, anticorps copb1, anticorps copb1.L, anticorps COPB1, anticorps Copb1

Sujet:

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa-type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte surface triglyceride lipase (PNPLA2) with the lipid droplet to mediate lipolysis (By similarity). Involved in the Golgi disassembly and reassembly processes during cell cycle. Involved in autophagy by playing a role in early endosome function. Plays a role in organellar compartmentalization of secretory compartments including endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN) and recycling endosomes, and in biosynthetic transport of CAV1. Promotes degradation of Nef cellular targets CD4 and MHC class I antigens by facilitating their trafficking to degradative compartments.

Aliases: Beta-coat protein antibody, Beta-COP antibody, betacop antibody, Coatomer beta subunit antibody, Coatomer protein complex subunit beta 1 antibody, Coatomer protein complex subunit beta antibody, Coatomer subunit beta antibody, COPB antibody, COPB_HUMAN antibody, Copb1 antibody, DKFZp761K102 antibody, FLJ10341 antibody

UniProt: P53618