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COPB1 anticorps (AA 2-200) (HRP)

COPB1 Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7148012
  • Antigène Voir toutes COPB1 Anticorps
    COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-200
    Reactivité
    • 50
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 50
    • 1
    Lapin
    Clonalité
    • 50
    • 1
    Polyclonal
    Conjugué
    • 18
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPB1 est conjugé à/à la HRP
    Application
    • 25
    • 22
    • 13
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Coatomer subunit beta protein (2-200AA)
    Isotype
    IgG
    Top Product
    Discover our top product COPB1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    COPB1 (Coatomer Protein Complex, Subunit beta 1 (COPB1))
    Autre désignation
    COPB1 (COPB1 Produits)
    Synonymes
    anticorps id:ibd5034, anticorps wu:fc66c05, anticorps zgc:92482, anticorps COPB1, anticorps DKFZp459K154, anticorps COPB, anticorps 2610019B04Rik, anticorps Rack2, anticorps Beta-COP, anticorps coatomer protein complex, subunit beta 1, anticorps coatomer protein complex subunit beta 1 L homeolog, anticorps coatomer protein complex subunit beta 1, anticorps copb1, anticorps copb1.L, anticorps COPB1, anticorps Copb1
    Sujet

    Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. Plays a functional role in facilitating the transport of kappa-type opioid receptor mRNAs into axons and enhances translation of these proteins. Required for limiting lipid storage in lipid droplets. Involved in lipid homeostasis by regulating the presence of perilipin family members PLIN2 and PLIN3 at the lipid droplet surface and promoting the association of adipocyte surface triglyceride lipase (PNPLA2) with the lipid droplet to mediate lipolysis (By similarity). Involved in the Golgi disassembly and reassembly processes during cell cycle. Involved in autophagy by playing a role in early endosome function. Plays a role in organellar compartmentalization of secretory compartments including endoplasmic reticulum (ER)-Golgi intermediate compartment (ERGIC), Golgi, trans-Golgi network (TGN) and recycling endosomes, and in biosynthetic transport of CAV1. Promotes degradation of Nef cellular targets CD4 and MHC class I antigens by facilitating their trafficking to degradative compartments.

    Aliases: Beta-coat protein antibody, Beta-COP antibody, betacop antibody, Coatomer beta subunit antibody, Coatomer protein complex subunit beta 1 antibody, Coatomer protein complex subunit beta antibody, Coatomer subunit beta antibody, COPB antibody, COPB_HUMAN antibody, Copb1 antibody, DKFZp761K102 antibody, FLJ10341 antibody

    UniProt
    P53618
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