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COPS7B anticorps (AA 1-157) (HRP)

COPS7B Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7148506
  • Antigène Voir toutes COPS7B Anticorps
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Épitope
    • 15
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-157
    Reactivité
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 30
    • 2
    Lapin
    Clonalité
    • 32
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp COPS7B est conjugé à/à la HRP
    Application
    • 23
    • 13
    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human COP9 signalosome complex subunit 7b protein (1-157AA)
    Isotype
    IgG
    Top Product
    Discover our top product COPS7B Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    COPS7B (COP9 Signalosome Complex Subunit 7b (COPS7B))
    Autre désignation
    COPS7B (COPS7B Produits)
    Synonymes
    anticorps MGC114836, anticorps D1Wsu66e, anticorps E130114M23, anticorps CSN7B, anticorps COP9 signalosome subunit 7B, anticorps COP9 signalosome subunit 7B S homeolog, anticorps Cops7b, anticorps COPS7B, anticorps cops7b.S
    Sujet

    Background: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

    Aliases: COP9 Complex Homolog Subunit 7b antibody, COP9 Constitutive Photomorphogenic Homolog Subunit 7b antibody, COP9 Signalasome Subunit 7b antibody, COP9 signalosome complex subunit 7b antibody, COPS7B antibody, CSN7B_HUMAN antibody, JAB1 Containing Signalosome Subunit 7b antibody, JAB1-containing signalosome subunit 7b antibody, SGN7b antibody, Signalosome subunit 7b antibody

    UniProt
    Q9H9Q2
    Pathways
    Cycle Cellulaire
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