CBP anticorps (AA 2217-2442)
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- Antigène Voir toutes CBP (CREBBP) Anticorps
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
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Épitope
- AA 2217-2442
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp CBP est non-conjugé
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Application
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human CREB-binding protein (2217-2442AA)
- Isotype
- IgG
- Top Product
- Discover our top product CREBBP Anticorps primaire
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- CBP (CREBBP) (CREB Binding Protein (CREBBP))
- Autre désignation
- CREBBP (CREBBP Produits)
- Sujet
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Background: Acetylates histones, giving a specific tag for transcriptional activation. Also acetylates non-histone proteins, like NCOA3 and FOXO1. Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Acetylates PCNA, acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902).
Aliases: CBP antibody, CBP_HUMAN antibody, CREB binding protein antibody, CREB-binding protein antibody, Crebbp antibody, Cyclic AMP responsive enhancer binding protein antibody, KAT3A antibody, RSTS antibody, RTS antibody, Rubinstein Taybi syndrome antibody
- UniProt
- Q92793
- Pathways
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
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