CRTC1 anticorps (AA 1-248) (Biotin)

N° du produit ABIN7148676

Détail du produit anti-CRTC1 anticorps (Biotin)

Antigène: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Épitope: AA 1-248

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human CREB-regulated transcription coactivator 1 protein (1-248AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CRTC1

Antigène: CRTC1 (CREB Regulated Transcription Coactivator 1 (CRTC1))

Autre désignation: CRTC1 (CRTC1 Produits)

Synonymes: anticorps MECT1, anticorps TORC-1, anticorps TORC1, anticorps WAMTP1, anticorps AI413414, anticorps Mect1, anticorps R74955, anticorps mKIAA0616, anticorps CRTC1, anticorps crtc1, anticorps fc68c05, anticorps pde4cb, anticorps si:ch211-255d18.1, anticorps si:ch211-255d18.8, anticorps wu:fc68c05, anticorps CREB regulated transcription coactivator 1, anticorps CREB regulated transcription coactivator 1b, anticorps CRTC1, anticorps Crtc1, anticorps crtc1, anticorps crtc1b

Sujet:

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). In the hippocampus, involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses. May be required for dendritic growth of developing cortical neurons (By similarity). In concert with SIK1, regulates the light-induced entrainment of the circadian clock. In response to light stimulus, coactivates the CREB-mediated transcription of PER1 which plays an important role in the photic entrainment of the circadian clock.

Aliases: KIAA0616 antibody, CREB regulated transcription coactivator 1 antibody, CREB-regulated transcription coactivator 1 antibody, CRTC1 antibody, CRTC1_HUMAN antibody, FLJ14027 antibody, MECT 1 antibody, Mucoepidermoid carcinoma translocated 1 antibody, Mucoepidermoid carcinoma translocated protein 1 antibody, TORC-1 antibody, TORC1 antibody, Transducer of CREB protein 1 antibody, Transducer of regulated cAMP response element binding protein 1 antibody, Transducer of regulated cAMP response element-binding protein (CREB) 1 antibody, Transducer of regulated cAMP response element-binding protein 1 antibody, WAMTP1 antibody

UniProt: Q6UUV9