CRTC2 anticorps (AA 180-372)

N° du produit ABIN7148679

Détail du produit anti-CRTC2 anticorps

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Épitope: AA 180-372

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRTC2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human CREB-regulated transcription coactivator 2 protein (180-372AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur CRTC2

Antigène: CRTC2 (CREB Regulated Transcription Coactivator 2 (CRTC2))

Autre désignation: CRTC2 (CRTC2 Produits)

Synonymes: anticorps CRTC2, anticorps TORC-2, anticorps TORC2, anticorps 4632407F12Rik, anticorps Torc2, anticorps mTORC2, anticorps RGD1308903, anticorps CREB regulated transcription coactivator 2, anticorps CRTC2, anticorps Crtc2

Sujet:

Background: Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).

Aliases: CREB regulated transcription coactivator 2 antibody, CREB-regulated transcription coactivator 2 antibody, CRTC2 antibody, CRTC2_HUMAN antibody, RP11-422P24.6 antibody, TORC-2 antibody, torc2 antibody, Transducer of CREB protein 2 antibody, Transducer of regulated cAMP response element-binding protein antibody, Transducer of regulated cAMP response element-binding protein (CREB) 2 antibody, Transducer of regulated cAMP response element-binding protein 2 antibody, Transducer of regulated CREB protein 2 antibody

UniProt: Q53ET0

Pathways: AMPK Signaling, Carbohydrate Homeostasis