Cyclin C anticorps (AA 240-283)

N° du produit ABIN7148838

Détail du produit anti-Cyclin C anticorps

Antigène: Cyclin C (CCNC)

Épitope: AA 240-283

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin C est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Cyclin-C protein (240-283AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Cyclin C

Antigène: Cyclin C (CCNC)

Autre désignation: CCNC (CCNC Produits)

Synonymes: anticorps CG1C_DROME, anticorps CG7281, anticorps CYCC, anticorps Cln3, anticorps Cyc-C, anticorps DmcycC, anticorps Dmel\\CG7281, anticorps SRB11, anticorps cycC, anticorps cyclinC, anticorps dTRAP33, anticorps fj11d06, anticorps wu:fj11d06, anticorps zgc:73078, anticorps Cyclin-C, anticorps CycC, anticorps AI451004, anticorps AU020987, anticorps CG1C, anticorps Cyclin C, anticorps cyclin C, anticorps cyclin C L homeolog, anticorps cyclin-C, anticorps CycC, anticorps ccnc, anticorps CCNC, anticorps Ccnc, anticorps ccnc.L, anticorps LOC5577815

Sujet:

Background: Component of the Mediator complex, a coactivator involved in regulated gene transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Binds to and activates cyclin-dependent kinase CDK8 that phosphorylates the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNAp II), which may inhibit the formation of a transcription initiation complex.

Aliases: ccnc antibody, CCNC_HUMAN antibody, CycC antibody, Cyclin C antibody, Cyclin-C antibody, hSRB11 antibody, OTTHUMP00000016897 antibody, SRB11 homolog antibody

UniProt: P24863

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha