DAPK2 anticorps (AA 222-370)
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- Antigène Voir toutes DAPK2 Anticorps
- DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
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Épitope
- AA 222-370
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DAPK2 est non-conjugé
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Souris
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Death-associated protein kinase 2 protein (222-370AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))
- Autre désignation
- DAPK2 (DAPK2 Produits)
- Synonymes
- anticorps drp1, anticorps drp-1, anticorps DAPK2, anticorps dapk2, anticorps DRP-1, anticorps DRP1, anticorps death-associated protein kinase 2 L homeolog, anticorps death associated protein kinase 2, anticorps death-associated protein kinase 2b, anticorps death-associated protein kinase 2, anticorps dapk2.L, anticorps DAPK2, anticorps dapk2b, anticorps dapk2, anticorps Dapk2
- Sujet
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Background: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Aliases: DAK2 antibody, DAP kinase 2 antibody, DAP kinase related protein 1 antibody, DAP kinase related protein 1 beta isoform antibody, DAP-kinase-related protein 1 antibody, DAPK2 antibody, DAPK2_HUMAN antibody, Death associated protein kinase 2 antibody, Death-associated protein kinase 2 antibody, DRP 1 antibody, DRP-1 antibody, DRP1 antibody, MGC119312 antibody
- UniProt
- Q9UIK4
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