DOCK1 anticorps (AA 1676-1865)
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- Antigène Voir toutes DOCK1 Anticorps
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
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Épitope
- AA 1676-1865
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp DOCK1 est non-conjugé
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Application
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
- Isotype
- IgG
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- Indications d'application
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
- Autre désignation
- DOCK1 (DOCK1 Produits)
- Synonymes
- anticorps DOCK180, anticorps ced5, anticorps 9130006G06Rik, anticorps AI854900, anticorps D630004B07Rik, anticorps RGD1566072, anticorps dedicator of cytokinesis 1, anticorps dedicator of cytokinesis protein 1, anticorps dedicator of cyto-kinesis 1, anticorps DOCK1, anticorps Dock1, anticorps dock1, anticorps CpipJ_CPIJ002759
- Sujet
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Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).
Aliases: 180 kDa protein downstream of CRK antibody, Ced5 antibody, Dedicator of Cytokinesis 1 antibody, Dedicator of cytokinesis protein 1 antibody, DOCK 1 antibody, DOCK 180 antibody, DOCK1 antibody, DOCK1_HUMAN antibody, DOCK180 antibody
- UniProt
- Q14185
- Pathways
- Signaling of Hepatocyte Growth Factor Receptor
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