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DOCK1 anticorps (AA 1676-1865)

DOCK1 Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7149579
  • Antigène Voir toutes DOCK1 Anticorps
    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
    Épitope
    • 15
    • 6
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1676-1865
    Reactivité
    • 30
    • 23
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 42
    • 1
    • 1
    • 1
    Lapin
    Clonalité
    • 44
    • 1
    Polyclonal
    Conjugué
    • 18
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp DOCK1 est non-conjugé
    Application
    • 15
    • 14
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Dedicator of cytokinesis protein 1 protein (1676-1865AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    DOCK1 (Dedicator of Cytokinesis 1 (DOCK1))
    Autre désignation
    DOCK1 (DOCK1 Produits)
    Synonymes
    anticorps DOCK180, anticorps ced5, anticorps 9130006G06Rik, anticorps AI854900, anticorps D630004B07Rik, anticorps RGD1566072, anticorps dedicator of cytokinesis 1, anticorps dedicator of cytokinesis protein 1, anticorps dedicator of cyto-kinesis 1, anticorps DOCK1, anticorps Dock1, anticorps dock1, anticorps CpipJ_CPIJ002759
    Sujet

    Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen (PubMed:19004829). Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 (PubMed:8657152).

    Aliases: 180 kDa protein downstream of CRK antibody, Ced5 antibody, Dedicator of Cytokinesis 1 antibody, Dedicator of cytokinesis protein 1 antibody, DOCK 1 antibody, DOCK 180 antibody, DOCK1 antibody, DOCK1_HUMAN antibody, DOCK180 antibody

    UniProt
    Q14185
    Pathways
    Signaling of Hepatocyte Growth Factor Receptor
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