DOCK3 anticorps (AA 1630-1934)

N° du produit ABIN7149587

Détail du produit anti-DOCK3 anticorps

Antigène: DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))

Épitope: AA 1630-1934

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK3 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DOCK3

Antigène: DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))

Autre désignation: DOCK3 (DOCK3 Produits)

Synonymes: anticorps MOCA, anticorps PBP, anticorps mKIAA0299, anticorps dedicator of cytokinesis 3, anticorps similar to dedicator of cytokinesis 3, anticorps dedicator of cytokinesis protein 3, anticorps dedicator of cyto-kinesis 3, anticorps DOCK3, anticorps LOC561387, anticorps dock3, anticorps LOC100474164, anticorps Dock3

Sujet:

Background: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).

Aliases: DOCK3 antibody, KIAA0299 antibody, MOCADedicator of cytokinesis protein 3 antibody, Modifier of cell adhesion antibody, Presenilin-binding protein antibody, PBP antibody

UniProt: Q8IZD9