DOCK7 anticorps (AA 1440-1671)

N° du produit ABIN7149599

Détail du produit anti-DOCK7 anticorps

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Épitope: AA 1440-1671

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK7 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:2000-1:5000, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DOCK7

Antigène: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Autre désignation: DOCK7 (DOCK7 Produits)

Synonymes: anticorps im:7145816, anticorps im:7157388, anticorps wu:fb93h07, anticorps ZIR2, anticorps 3110056M06Rik, anticorps Gm430, anticorps m, anticorps mKIAA1771, anticorps dedicator of cytokinesis 7, anticorps dedicator of cytokinesis protein 7, anticorps dedicator of cytokinesis 6, anticorps DOCK7, anticorps dock7, anticorps NAEGRDRAFT_56982, anticorps LOC100185115, anticorps dock6, anticorps Dock7

Sujet:

Background: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

Aliases: DOCK7 antibody, KIAA1771Dedicator of cytokinesis protein 7 antibody

UniProt: Q96N67