Transmembrane 7 Superfamily Member 4 (TM7SF4) (AA 119-209) anticorps

N° du produit ABIN7149663

Détail du produit

Antigène: Transmembrane 7 Superfamily Member 4 (TM7SF4)

Épitope: AA 119-209

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Dendritic cell-specific transmembrane protein (119-209AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Transmembrane 7 Superfamily Member 4 (TM7SF4)

Autre désignation: DCSTAMP (TM7SF4 Produits)

Synonymes: anticorps Tm7sf4, anticorps TM7SF4, anticorps FIND, anticorps hDC-STAMP, anticorps 4833414I07Rik, anticorps DC-STAMP, anticorps mDC-STAMP, anticorps dendrocyte expressed seven transmembrane protein, anticorps Dcstamp, anticorps DCSTAMP

Sujet:

Background: Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

Aliases: DC-STAMP antibody, DCSTAMP antibody, DCSTP_HUMAN antibody, Dendritic cell-specific transmembrane protein antibody, Dendrocyte-expressed seven transmembrane protein antibody, FIND antibody, hDC-STAMP antibody, IL-Four INDuced antibody, IL-four-induced protein antibody, Transmembrane 7 superfamily member 4 antibody

UniProt: Q9H295