ADAM15 anticorps (AA 207-452)

N° du produit ABIN7150042

Détail du produit anti-ADAM15 anticorps

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Épitope: AA 207-452

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ADAM15 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ADAM15

Antigène: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Autre désignation: ADAM15 (ADAM15 Produits)

Synonymes: anticorps ADAM15, anticorps mdc15, anticorps MDC15, anticorps metargidin, anticorps tMDCVI, anticorps ADAM metallopeptidase domain 15, anticorps ADAM metallopeptidase domain 15 L homeolog, anticorps a disintegrin and metallopeptidase domain 15 (metargidin), anticorps ADAM15, anticorps adam15.L, anticorps adam15, anticorps Adam15

Sujet:

Background: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

Aliases: A disintegrin and metalloproteinase domain 15 (metargidin) antibody, A disintegrin and metalloproteinase domain 15 antibody, ADA15_HUMAN antibody, ADAM 15 antibody, ADAM metallopeptidase domain 15 antibody, Adam15 antibody, and cysteine-rich protein 15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, disintegrin-like antibody, EC 3.4.24. antibody, MDC 15 antibody, MDC-15 antibody, MDC15 antibody, Metalloprotease RGD disintegrin protein antibody, Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody, Metalloproteinase-like antibody, Metargidin antibody

UniProt: Q13444