POLH anticorps (AA 408-609) (Biotin)

N° du produit ABIN7150248

Détail du produit anti-POLH anticorps (Biotin)

Antigène: POLH (Polymerase (DNA Directed), eta (POLH))

Épitope: AA 408-609

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLH est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DNA polymerase eta protein (408-609AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POLH

Antigène: POLH (Polymerase (DNA Directed), eta (POLH))

Autre désignation: POLH (POLH Produits)

Synonymes: anticorps POLH, anticorps fc50a12, anticorps wu:fc50a12, anticorps zgc:136881, anticorps zgc:152642, anticorps RAD30, anticorps RAD30A, anticorps XP-V, anticorps XPV, anticorps polymerase (DNA directed), eta S homeolog, anticorps DNA polymerase eta, anticorps polymerase (DNA directed), eta, anticorps putative DNA polymerase eta, anticorps polymerase (DNA directed), eta (RAD 30 related), anticorps polh.S, anticorps POLH, anticorps polh, anticorps Tb10.70.6190, anticorps LINJ_21_0690, anticorps Polh, anticorps LOC100443019

Sujet:

Background: DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Plays an important role in the repair of UV-induced pyrimidine dimers. Depending on the context, it inserts the correct base, but causes frequent base transitions and transversions. May play a role in hypermutation at immunoglobulin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but does not have lyase activity. Targets POLI to replication foci.

Aliases: DNA polymerase eta antibody, FLJ16395 antibody, FLJ21978 antibody, Polh antibody, POLH_HUMAN antibody, polymerase DNA directed eta antibody, RAD30 antibody, RAD30 homolog A antibody, RAD30A antibody, Xeroderma pigmentosum variant type protein antibody, XP V antibody, XPV antibody

UniProt: Q9Y253

Pathways: Réparation de l'ADN