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POLI anticorps (AA 458-711)

POLI Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7150251
  • Antigène Voir toutes POLI Anticorps
    POLI (Polymerase (DNA Directed) iota (POLI))
    Épitope
    • 15
    • 8
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 458-711
    Reactivité
    • 40
    • 26
    • 11
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 52
    • 3
    Lapin
    Clonalité
    • 52
    • 3
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp POLI est non-conjugé
    Application
    • 28
    • 26
    • 16
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human DNA polymerase iota protein (458-711AA)
    Isotype
    IgG
    Top Product
    Discover our top product POLI Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    POLI (Polymerase (DNA Directed) iota (POLI))
    Autre désignation
    POLI (POLI Produits)
    Synonymes
    anticorps poli, anticorps wu:fc27h11, anticorps zgc:110185, anticorps GB12093, anticorps NV16187, anticorps RAD30B, anticorps RAD3OB, anticorps Rad30b, anticorps DNA polymerase iota, anticorps polymerase (DNA directed) iota, anticorps polymerase (DNA directed), iota, anticorps POLI, anticorps poli, anticorps LOC551219, anticorps AFUA_4G11140, anticorps LOC5568276, anticorps Pol-iota, anticorps Poli
    Sujet

    Background: Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5\'-deoxyribose phosphate at abasic sites, but may not have lyase activity.

    Aliases: DNA polymerase iota antibody, Eta 2 antibody, Eta2 antibody, POLI antibody, POLI_HUMAN antibody, Polymerase (DNA directed) iota antibody, RAD 30B antibody, RAD30 homolog B antibody, RAD30, S. cerevisiae, homolog of antibody, RAD30B antibody, RAD3OB antibody

    UniProt
    Q9UNA4
    Pathways
    Réparation de l'ADN
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