SATB2 anticorps (AA 228-369)

N° du produit ABIN7150394

Détail du produit anti-SATB2 anticorps

Antigène: SATB2 (SATB Homeobox 2 (SATB2))

Épitope: AA 228-369

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SATB2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Antigen Affinity purified & Affinity purified

Immunogène: Recombinant Human DNA-binding protein SATB2 protein (228-369AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SATB2

Antigène: SATB2 (SATB Homeobox 2 (SATB2))

Autre désignation: SATB2 (SATB2 Produits)

Synonymes: anticorps RGD1562369, anticorps mKIAA1034, anticorps SATB homeobox 2, anticorps special AT-rich sequence binding protein 2, anticorps SATB2, anticorps satb2, anticorps Satb2

Sujet:

Background: Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons (UL1) specific genetic program and for the inactivation of deep-layer neurons (DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation.

Aliases: DNA binding protein SATB2 antibody, DNA-binding protein SATB2 antibody, FLJ21474 antibody, FLJ32076 antibody, GLSS antibody, KIAA1034 antibody, MGC119474 antibody, MGC119477 antibody, SATB family member 2 antibody, SATB homeobox 2 antibody, SATB2 antibody, SATB2_HUMAN antibody, Special AT rich sequence binding protein 2 antibody, Special AT-rich sequence-binding protein 2 antibody

UniProt: Q9UPW6