POLR2D anticorps (AA 1-142)

N° du produit ABIN7150434

Détail du produit anti-POLR2D anticorps

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Épitope: AA 1-142

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp POLR2D est non-conjugé

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur POLR2D

Antigène: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Autre désignation: POLR2D (POLR2D Produits)

Synonymes: anticorps wu:fa95b11, anticorps zgc:110435, anticorps HSRBP4, anticorps HSRPB4, anticorps RBP4, anticorps RPB16, anticorps 2310002G05Rik, anticorps 2610028L19Rik, anticorps RNA polymerase II subunit D, anticorps DNA-directed RNA polymerase II 16 kDa polypeptide, anticorps polymerase (RNA) II (DNA directed) polypeptide D, anticorps Polr2d, anticorps CpipJ_CPIJ006734, anticorps UREG_01395, anticorps LOC100282338, anticorps polr2d, anticorps POLR2D

Sujet:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.

Aliases: DNA directed RNA polymerase II 16 kDa polypeptide antibody, DNA directed RNA polymerase II subunit D antibody, DNA directed RNA polymerase II subunit RPB4 antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, DNA-directed RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II subunit rpb4 antibody, HSRBP4 antibody, HSRPB4 antibody, polr2d antibody, polymerase RNA II DNA directed polypeptide D antibody, RBP4 antibody, RNA polymerase II 16 kDa subunit antibody, RNA polymerase II subunit B4 antibody, RNA polymerase II subunit D antibody, RNA polymerase II subunit hsRBP4 antibody, RPB16 antibody, RPB4_HUMAN antibody

UniProt: O15514

Pathways: Regulatory RNA Pathways