DAD1 anticorps (AA 1-113)

N° du produit ABIN7150599

Détail du produit anti-DAD1 anticorps

Antigène: DAD1 (Defender Against Cell Death 1 (DAD1))

Épitope: AA 1-113

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DAD1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 protein (1-113AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DAD1

Antigène: DAD1 (Defender Against Cell Death 1 (DAD1))

Autre désignation: DAD1 (DAD1 Produits)

Synonymes: anticorps NV18456, anticorps dad1, anticorps DAD1, anticorps ost2, anticorps DAD-1, anticorps si:ch211-9d9.5, anticorps OST2, anticorps AI323713, anticorps DEFENDER AGAINST APOPTOTIC DEATH 1, anticorps F3C3.14, anticorps F3C3_14, anticorps dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1, anticorps defender against cell death 1, anticorps hypothetical protein, anticorps defender against cell death 1 S homeolog, anticorps Defender against death (DAD family) protein, anticorps false DAD1, anticorps Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit dad-1, anticorps LOC100115214, anticorps DAD1, anticorps dad1, anticorps CC1G_00458, anticorps CpipJ_CPIJ003512, anticorps PGTG_09898, anticorps Dad1, anticorps dad1.S, anticorps ATDAD1, anticorps fdad1, anticorps dad-1

Sujet:

Background: Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc3Man9GlcNAc2 in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (PubMed:22467853). N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity (By similarity). Required for the assembly of both SST3A- and SS3B-containing OST complexes. Loss of the DAD1 protein triggers apoptosis (PubMed:22467853).

Aliases: DAD 1 antibody, DAD-1 antibody, dad1 antibody, DAD1_HUMAN antibody, Defender against cell death 1 antibody, Dolichyl diphosphooligosaccharide protein glycosyltransferase subunit DAD1 antibody, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 antibody, Oligosaccharyl transferase subunit DAD1 antibody, OST 2 antibody, OST2 antibody

UniProt: P61803