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Mre11 anticorps (AA 1-205)

MRE11A Reactivité: Humain ELISA, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7150624
  • Antigène Voir toutes Mre11 (MRE11A) Anticorps
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Épitope
    • 21
    • 15
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-205
    Reactivité
    • 79
    • 55
    • 42
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 93
    • 5
    Lapin
    Clonalité
    • 85
    • 13
    Polyclonal
    Conjugué
    • 46
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Cet anticorp Mre11 est non-conjugé
    Application
    • 73
    • 33
    • 26
    • 26
    • 18
    • 15
    • 14
    • 11
    • 6
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Double-strand break repair protein MRE11A protein (1-205AA)
    Isotype
    IgG
    Top Product
    Discover our top product MRE11A Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))
    Autre désignation
    MRE11 (MRE11A Produits)
    Synonymes
    anticorps wu:faa63d12, anticorps zgc:64018, anticorps Mre11, anticorps Mre11b, anticorps ATLD, anticorps HNGS1, anticorps MRE11, anticorps MRE11B, anticorps MRE11 homolog A, double strand break repair nuclease, anticorps MRE11 homolog, double strand break repair nuclease, anticorps MRE11A homolog A, double strand break repair nuclease, anticorps mre11a, anticorps MRE11, anticorps Mre11a
    Sujet

    Background: Component of the MRN complex, which plays a central role in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity and meiosis. The complex possesses single-strand endonuclease activity and double-strand-specific 3\\\'-5\\\' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity. This could facilitate searches for short or long regions of sequence homology in the recombining DNA templates, and may also stimulate the activity of DNA ligases and/or restrict the nuclease activity of MRE11A to prevent nucleolytic degradation past a given point (PubMed:9651580, PubMed:9590181, PubMed:9705271, PubMed:11741547). The complex may also be required for DNA damage signaling via activation of the ATM kinase (PubMed:15064416). In telomeres the MRN complex may modulate t-loop formation (PubMed:10888888).

    Aliases: AT like disease antibody, Ataxia telangiectasia disorder like antibody, ATLD antibody, DNA recombination and repair protein antibody, Double strand break repair protein MRE11A antibody, Double-strand break repair protein MRE11A antibody, endo/exonuclease Mre11 antibody, HNGS1 antibody, meiotic recombination (S. cerevisiae) 11 homolog A antibody, Meiotic recombination 11 homolog 1 antibody, meiotic recombination 11 homolog A (S. cerevisiae) antibody, Meiotic recombination 11 homolog A antibody, M mMRE11A antibody, Mre 11 antibody, MRE 11a antibody, MRE 11b antibody, MRE11 homolog 1 antibody, MRE11 homolog A antibody, MRE11 homolog double strand break repair nuclease antibody, MRE11 meiotic recombination 11 homolog A (S. cerevisiae) antibody, MRE11 meiotic recombination 11 homolog A antibody, MRE11_HUMAN antibody, MRE11A antibody, MRE11b antibody, OTTHUMP00000236830 antibody, OTTHUMP00000236831 antibody, OTTHUMP00000236832 antibody, OTTHUMP00000236833 antibody

    UniProt
    P49959
    Pathways
    Réparation de l'ADN
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