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DMRT1 anticorps (AA 195-363)

DMRT1 Reactivité: Humain WB, ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7150637
  • Antigène Voir toutes DMRT1 Anticorps
    DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
    Épitope
    • 8
    • 8
    • 6
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 195-363
    Reactivité
    • 36
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 29
    • 8
    Lapin
    Clonalité
    • 31
    • 6
    Polyclonal
    Conjugué
    • 23
    • 4
    • 3
    • 3
    • 2
    • 2
    Cet anticorp DMRT1 est non-conjugé
    Application
    • 33
    • 17
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain, Souris
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Doublesex- and mab-3-related transcription factor 1 protein (195-363AA)
    Isotype
    IgG
  • Indications d'application
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    DMRT1 (Doublesex and Mab-3 Related Transcription Factor 1 (DMRT1))
    Autre désignation
    DMRT1 (DMRT1 Produits)
    Synonymes
    anticorps DMT1, anticorps DMRT1, anticorps zgc:136676, anticorps dmrt1, anticorps dmrt1-alpha, anticorps dmt1, anticorps dmrt1-beta, anticorps xdmrt1, anticorps doublesex and mab-3 related transcription factor 1, anticorps doublesex and mab-3 related transcription factor 1 L homeolog, anticorps doublesex and mab-3 related transcription factor 1 S homeolog, anticorps DMRT1, anticorps Dmrt1, anticorps dmrt1, anticorps dmrt1.L, anticorps dmrt1.S
    Sujet

    Background: Transcription factor that plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. Plays a central role in spermatogonia by inhibiting meiosis in undifferentiated spermatogonia and promoting mitosis, leading to spermatogonial development and allowing abundant and continuous production of sperm. Acts both as a transcription repressor and activator: prevents meiosis by restricting retinoic acid (RA)-dependent transcription and repressing STRA8 expression and promotes spermatogonial development by activating spermatogonial differentiation genes, such as SOHLH1. Also plays a key role in postnatal sex maintenance by maintaining testis determination and preventing feminization: represses transcription of female promoting genes such as FOXL2 and activates male-specific genes. May act as a tumor suppressor. May also play a minor role in oogenesis (By similarity).

    Aliases: CT154 antibody, DM domain expressed in testis 1 antibody, DM domain expressed in testis protein 1 antibody, DM domain gene expressed in testis antibody, DMRT 1 antibody, dmrt1 antibody, DMRT1_HUMAN antibody, DMT 1 antibody, DMT1 antibody, Doublesex and mab 3 related transcription factor 1 antibody, Doublesex- and mab-3-related transcription factor 1 antibody

    UniProt
    Q9Y5R6
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