DSCAM anticorps (AA 1711-1867)

N° du produit ABIN7150649

Détail du produit anti-DSCAM anticorps

Antigène: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Épitope: AA 1711-1867

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DSCAM est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur DSCAM

Antigène: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Autre désignation: DSCAM (DSCAM Produits)

Synonymes: anticorps CHD2-42, anticorps CHD2-52, anticorps Dscam, anticorps DSCAM, anticorps chd2-42, anticorps chd2-52, anticorps dscam, anticorps GB15141, anticorps 4932410A21Rik, anticorps 43Bc, anticorps CG17800, anticorps CT39257, anticorps DScam, anticorps DmDscam, anticorps Dm_2R:13612, anticorps Dmel\\CG17800, anticorps Dscam-hv, anticorps Dscam1, anticorps FBgn0033159, anticorps Neu1, anticorps dScam, anticorps l(2)05518, anticorps l(2)43Bc, anticorps p270, anticorps DS cell adhesion molecule, anticorps Down syndrome cell adhesion molecule, anticorps Down syndrome cell adhesion molecule a, anticorps Down syndrome cell adhesion molecule 1, anticorps Down syndrome cell adhesion molecule-like protein Dscam2, anticorps down syndrome cell adhesion molecule, anticorps Down syndrome cell adhesion molecule L homeolog, anticorps DSCAM, anticorps Dscam, anticorps dscam, anticorps dscama, anticorps Dscam1, anticorps LOC5573626, anticorps CpipJ_CPIJ006173, anticorps dscam.L

Sujet:

Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).

Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody

UniProt: O60469

Pathways: Regulation of Cell Size