Dynamin 1-Like anticorps (AA 496-710)

N° du produit ABIN7150829

Détail du produit anti-Dynamin 1-Like anticorps

Antigène: Dynamin 1-Like (DNM1L)

Épitope: AA 496-710

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dynamin 1-Like est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Dynamin-1-like protein (496-710AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur Dynamin 1-Like

Antigène: Dynamin 1-Like (DNM1L)

Autre désignation: DNM1L (DNM1L Produits)

Sujet:

Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.

Aliases: DLP1 antibody, dnm1l antibody, DNM1L_HUMAN antibody, Dnm1p/Vps1p-like protein antibody, dnml1 antibody, DRP1 antibody, DVLP antibody, Dymple antibody, Dynamin 1 like antibody, Dynamin family member proline-rich carboxyl-terminal domain less antibody, Dynamin like protein antibody, Dynamin related protein 1 antibody, Dynamin-1-like protein antibody, Dynamin-like protein 4 antibody, Dynamin-like protein antibody, Dynamin-like protein IV antibody, Dynamin-related protein 1 antibody, DYNIV 11 antibody, EMPF antibody, EMPF1 antibody, FLJ41912 antibody, HdynIV antibody, VPS1 antibody

UniProt: O00429