PIAS3 anticorps (AA 399-628)

N° du produit ABIN7150969

Détail du produit anti-PIAS3 anticorps

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Épitope: AA 399-628

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PIAS3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur PIAS3

Antigène: PIAS3 (Protein Inhibitor of Activated STAT, 3 (PIAS3))

Autre désignation: PIAS3 (PIAS3 Produits)

Synonymes: anticorps PIAS3, anticorps Pias3l, anticorps ZMIZ5, anticorps protein inhibitor of activated STAT 3, anticorps protein inhibitor of activated STAT, 3, anticorps protein inhibitor of activated STAT 3 L homeolog, anticorps PIAS3, anticorps pias3, anticorps Pias3, anticorps pias3.L

Sujet:

Background: Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

Aliases: E3 SUMO protein ligase PIAS 3 antibody, E3 SUMO protein ligase PIAS3 antibody, E3 SUMO-protein ligase PIAS3 antibody, FLJ14651 antibody, OTTHUMP00000015586 antibody, OTTHUMP00000015587 antibody, PIAS 3 antibody, Pias3 antibody, PIAS3 protein antibody, PIAS3_HUMAN antibody, Protein inhibitor of activated STAT 3 antibody, Protein inhibitor of activated STAT protein 3 antibody, Protein inhibitor of activated STAT3 antibody, Zinc finger MIZ type containing 5 antibody, ZMIZ 5 antibody, ZMIZ5 antibody

UniProt: Q9Y6X2

Pathways: Signalistation JAK/STAT