ARIH2 anticorps (AA 43-360)

N° du produit ABIN7150983

Détail du produit anti-ARIH2 anticorps

Antigène: ARIH2 (protein ariadne-2 homolog (ARIH2))

Épitope: AA 43-360

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARIH2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase ARIH2 protein (43-360AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:2000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ARIH2

Antigène: ARIH2 (protein ariadne-2 homolog (ARIH2))

Autre désignation: ARIH2 (ARIH2 Produits)

Synonymes: anticorps ARI2, anticorps TRIAD1, anticorps AI843547, anticorps UIP48, anticorps wu:fa09c12, anticorps zgc:64093, anticorps ariadne RBR E3 ubiquitin protein ligase 2, anticorps ariadne RBR E3 ubiquitin protein ligase 2 L homeolog, anticorps ariadne homolog 2 (Drosophila), anticorps ARIH2, anticorps Arih2, anticorps arih2.L, anticorps arih2

Sujet:

Background: E3 ubiquitin-protein ligase, which catalyzes ubiquitination of target proteins together with ubiquitin-conjugating enzyme E2 UBE2L3 (PubMed:16118314, PubMed:17646546, PubMed:19340006, PubMed:24076655). Acts as an atypical E3 ubiquitin-protein ligase by working together with cullin-5-RING ubiquitin ligase complex (ECS complex, also named CRL5 complex) and initiating ubiquitination of ECS substrates: associates with ECS complex and specifically mediates addition of the first ubiquitin on ECS targets (By similarity). The initial ubiquitin is then elongated (By similarity). E3 ubiquitin-protein ligase activity is activated upon binding to neddylated form of the ECS complex (PubMed:24076655). Mediates \\\'Lys-6\\\', \\\'Lys-48\\\'-and \\\'Lys-63\\\'-linked polyubiquitination (PubMed:16118314, PubMed:17646546, PubMed:19340006). May play a role in myelopoiesis (PubMed:19340006).

Aliases: HT005 antibody, all trans retinoic acid inducible RING finger antibody, Ari 2 antibody, Ari-2 antibody, ARI2 antibody, ARI2_HUMAN antibody, Ariadne 2 antibody, Ariadne 2 protein homolog antibody, ariadne homolog 2 (Drosophila) antibody, ariadne homolog 2 antibody, Ariadne RBR E3 ubiquitin protein ligase 2 antibody, ARIH 2 antibody, Arih2 antibody, E3 ubiquitin protein ligase ARIH2 antibody, E3 ubiquitin-protein ligase ARIH2 antibody, protein ariadne 2 homolog antibody, Protein ariadne-2 homolog antibody, Triad 1 antibody, TRIAD1 antibody, Triad1 protein antibody, UIP48 antibody

UniProt: O95376