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RNF4 anticorps (AA 471-724) (Biotin)

RNF4 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7150992
  • Antigène Voir toutes RNF4 Anticorps
    RNF4 (Ring Finger Protein 4 (RNF4))
    Épitope
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 471-724
    Reactivité
    • 18
    • 3
    • 2
    Humain
    Hôte
    • 17
    • 2
    Lapin
    Clonalité
    • 18
    • 1
    Polyclonal
    Conjugué
    • 13
    • 3
    • 2
    • 1
    Cet anticorp RNF4 est conjugé à/à la Biotin
    Application
    • 10
    • 9
    • 4
    • 2
    • 1
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human E3 ubiquitin-protein ligase BRE1B protein (471-724AA)
    Isotype
    IgG
    Top Product
    Discover our top product RNF4 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNF4 (Ring Finger Protein 4 (RNF4))
    Autre désignation
    RNF4 (RNF4 Produits)
    Synonymes
    anticorps SLX5, anticorps SNURF, anticorps AU018689, anticorps Gtrgeo8, anticorps ring finger protein 4, anticorps RNF4, anticorps Rnf4
    Sujet

    Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \'Lys-120\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \'Lys-4\' and \'Lys-79\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes.

    Aliases: 95 kDa retinoblastoma associated protein antibody, 95 kDa retinoblastoma protein binding protein antibody, 95 kDa retinoblastoma-associated protein antibody, BRE 1B antibody, BRE1 B antibody, BRE1 E3 ubiquitin ligase homolog B antibody, BRE1-B antibody, BRE1B antibody, BRE1B_HUMAN antibody, DKFZp686K191 antibody, E3 ubiquitin protein ligase BRE1B antibody, E3 ubiquitin-protein ligase BRE1B antibody, KIAA0661 antibody, MGC13051 antibody, Rb associated protein antibody, RBP 95 antibody, RBP95 antibody, RING finger protein 40 antibody, Ring finger protein 40 E3 ubiquitin protein ligase antibody, RNF 40 antibody, Rnf40 antibody, STARING antibody

    UniProt
    O75150
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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