MSL2 anticorps (AA 341-473) (Biotin)

N° du produit ABIN7151073

Détail du produit anti-MSL2 anticorps (Biotin)

Antigène: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Épitope: AA 341-473

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MSL2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase MSL2 protein (341-473AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MSL2

Antigène: MSL2 (Male-Specific Lethal 2 Homolog (MSL2))

Autre désignation: MSL2 (MSL2 Produits)

Synonymes: anticorps MSL-2, anticorps MSL2L1, anticorps RNF184, anticorps E130103E02Rik, anticorps Msl2l1, anticorps Rnf184, anticorps RGD1310355, anticorps MSL complex subunit 2, anticorps male-specific lethal 2 homolog (Drosophila), anticorps MSL2, anticorps Msl2

Sujet:

Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at \'Lys-35\' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at \'Lys-4\' (H3K4me) and \'Lys-79\' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.

Aliases: Male specific lethal 2 homolog (Drosophila) antibody, Male specific lethal 2 homolog 1 antibody, Male specific lethal 2 homolog antibody, Male specific lethal 2 like 1 antibody, Male-specific lethal 2 homolog antibody, Male-specific lethal 2-like 1 antibody, Male-specific lethal-2 homolog 1 antibody, MSL-2 antibody, MSL2 antibody, MSL2-like 1 antibody, MSL2_HUMAN antibody, MSL2L1 antibody, Ring finger protein 184 antibody

UniProt: Q9HCI7