MSL2 anticorps (AA 341-473) (HRP)
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- Antigène Voir toutes MSL2 Anticorps
- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
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Épitope
- AA 341-473
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MSL2 est conjugé à/à la HRP
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human E3 ubiquitin-protein ligase MSL2 protein (341-473AA)
- Isotype
- IgG
- Top Product
- Discover our top product MSL2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- MSL2 (Male-Specific Lethal 2 Homolog (MSL2))
- Autre désignation
- MSL2 (MSL2 Produits)
- Synonymes
- anticorps MSL-2, anticorps MSL2L1, anticorps RNF184, anticorps E130103E02Rik, anticorps Msl2l1, anticorps Rnf184, anticorps RGD1310355, anticorps MSL complex subunit 2, anticorps male-specific lethal 2 homolog (Drosophila), anticorps MSL2, anticorps Msl2
- Sujet
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Background: Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at \'Lys-35\' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at \'Lys-4\' (H3K4me) and \'Lys-79\' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1.
Aliases: Male specific lethal 2 homolog (Drosophila) antibody, Male specific lethal 2 homolog 1 antibody, Male specific lethal 2 homolog antibody, Male specific lethal 2 like 1 antibody, Male-specific lethal 2 homolog antibody, Male-specific lethal 2-like 1 antibody, Male-specific lethal-2 homolog 1 antibody, MSL-2 antibody, MSL2 antibody, MSL2-like 1 antibody, MSL2_HUMAN antibody, MSL2L1 antibody, Ring finger protein 184 antibody
- UniProt
- Q9HCI7
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