MYLIP anticorps (AA 266-445)

N° du produit ABIN7151076

Détail du produit anti-MYLIP anticorps

Antigène: MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))

Épitope: AA 266-445

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYLIP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Réactivité croisée: Humain

Purification: Antigen Affinity Purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase MYLIP protein (266-445AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MYLIP

Antigène: MYLIP (Myosin Regulatory Light Chain Interacting Protein (MYLIP))

Autre désignation: MYLIP (MYLIP Produits)

Synonymes: anticorps IDOL, anticorps MIR, anticorps 9430057C20Rik, anticorps Mir, anticorps mylip, anticorps wu:fj36b03, anticorps zgc:55987, anticorps MYLIP, anticorps mir, anticorps zgc:153767, anticorps myosin regulatory light chain interacting protein, anticorps myosin regulatory light chain interacting protein a, anticorps myosin regulatory light chain interacting protein L homeolog, anticorps myosin regulatory light chain interacting protein b, anticorps MYLIP, anticorps Mylip, anticorps mylipa, anticorps mylip.L, anticorps mylip, anticorps mylipb

Sujet:

Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC), LDLR, VLDLR and LRP8. Activity depends on E2 enzymes of the UBE2D family. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimulated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellular cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

Aliases: BM-023 antibody, BZF1 antibody, E3 ubiquitin protein ligase MYLIP antibody, E3 ubiquitin-protein ligase MYLIP antibody, Idol antibody, Inducible degrader of the LDL-receptor antibody, Lipoprotein receptor antibody, MIR antibody, MYLIP antibody, MYLIP_HUMAN antibody, Myosin regulatory light chain interacting protein antibody, PP5242 antibody

UniProt: Q8WY64