RBBP6 anticorps (AA 51-97)

N° du produit ABIN7151111

Détail du produit anti-RBBP6 anticorps

Antigène: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Épitope: AA 51-97

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBBP6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase RBBP6 protein (51-97AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur RBBP6

Antigène: RBBP6 (Retinoblastoma Binding Protein 6 (RBBP6))

Autre désignation: RBBP6 (RBBP6 Produits)

Synonymes: anticorps MY038, anticorps P2P-R, anticorps PACT, anticorps RBQ-1, anticorps SNAMA, anticorps 4933422O15Rik, anticorps AI316869, anticorps BB233631, anticorps C030034J04Rik, anticorps C77662, anticorps rbbp6, anticorps MGC75882, anticorps RBBP6, anticorps im:7158869, anticorps rbbp6l, anticorps RB binding protein 6, ubiquitin ligase, anticorps retinoblastoma binding protein 6, ubiquitin ligase, anticorps retinoblastoma binding protein 6, anticorps RBBP6, anticorps Rbbp6, anticorps rbbp6

Sujet:

Background: E3 ubiquitin-protein ligase which promotes ubiquitination of YBX1, leading to its degradation by the proteasome (PubMed:18851979). May play a role as a scaffold protein to promote the assembly of the p53/TP53-MDM2 complex, resulting in increase of MDM2-mediated ubiquitination and degradation of p53/TP53, may function as negative regulator of p53/TP53, leading to both apoptosis and cell growth (By similarity). Regulates DNA-replication and the stability of chromosomal common fragile sites (CFSs) in a ZBTB38- and MCM10-dependent manner. Controls ZBTB38 protein stability and abundance via ubiquitination and proteasomal degradation, and ZBTB38 in turn negatively regulates the expression of MCM10 which plays an important role in DNA-replication (PubMed:24726359).

Aliases: DKFZp686P0638 antibody, DKFZp761B2423 antibody, E3 ubiquitin-protein ligase RBBP6 antibody, MY038 antibody, P2P R antibody, P2PR antibody, p53 associated cellular protein of testis antibody, p53-associated cellular protein of testis antibody, p53-associated cellular protein, testis-derived antibody, PACT antibody, Proliferation potential related protein antibody, Proliferation potential-related protein antibody, Protein P2P R antibody, Protein P2P-R antibody, Protein P2PR antibody, Protein RBQ 1 antibody, Protein RBQ1 antibody, RB binding protein 6, ubiquitin ligase antibody, RB binding Q protein 1 antibody, RBBP 6 antibody, Rbbp6 antibody, RBBP6_HUMAN antibody, RBQ 1 antibody, RBQ-1 antibody, RBQ1 antibody, Retinoblastoma binding protein 6 isoform 3 antibody, Retinoblastoma binding Q protein 1 antibody, Retinoblastoma-binding protein 6 antibody, Retinoblastoma-binding Q protein 1 antibody, SNAMA antibody, SNAMA, Drosophila, homolog of antibody

UniProt: Q7Z6E9

Pathways: Regulatory RNA Pathways