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RNF128 anticorps (AA 229-400) (Biotin)

RNF128 Reactivité: Humain ELISA Hôte: Lapin Polyclonal Biotin
N° du produit ABIN7151139
  • Antigène Voir toutes RNF128 Anticorps
    RNF128 (Ring Finger Protein 128 (RNF128))
    Épitope
    • 7
    • 5
    • 4
    • 2
    • 1
    AA 229-400
    Reactivité
    • 35
    • 21
    • 19
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Humain
    Hôte
    • 35
    Lapin
    Clonalité
    • 35
    Polyclonal
    Conjugué
    • 13
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF128 est conjugé à/à la Biotin
    Application
    • 31
    • 13
    • 11
    • 4
    • 2
    • 1
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human E3 ubiquitin-protein ligase RNF128 protein (229-400AA)
    Isotype
    IgG
    Top Product
    Discover our top product RNF128 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    RNF128 (Ring Finger Protein 128 (RNF128))
    Autre désignation
    RNF128 (RNF128 Produits)
    Synonymes
    anticorps rnf128, anticorps wu:fb57h05, anticorps zgc:77843, anticorps 1300002C13Rik, anticorps AI987883, anticorps GRAIL, anticorps Greul1, anticorps RGD1566282, anticorps grail, anticorps greul1, anticorps ring finger protein 128a, anticorps ring finger protein 128, E3 ubiquitin protein ligase, anticorps ring finger protein 128, anticorps ring finger protein 128, E3 ubiquitin protein ligase L homeolog, anticorps rnf128a, anticorps RNF128, anticorps Rnf128, anticorps rnf128.L
    Sujet

    Background: E3 ubiquitin-protein ligase that catalyzes \'Lys-48\'- and \'Lys-63\'-linked polyubiquitin chains formation. Functions as an inhibitor of cytokine gene transcription. Inhibits IL2 and IL4 transcription, thereby playing an important role in the induction of the anergic phenotype, a long-term stable state of T-lymphocyte unresponsiveness to antigenic stimulation associated with the blockade of interleukin production. Ubiquitinates ARPC5 with \'Lys-48\' linkages and COR1A with \'Lys-63\' linkages leading to their degradation, down-regulation of these cytosleletal components results in impaired lamellipodium formation and reduced accumulation of F-actin at the immunological synapse. Functions in the patterning of the dorsal ectoderm, sensitizes ectoderm to respond to neural-inducing signals.

    Aliases: E3 ubiquitin protein ligase RNF128 antibody, E3 ubiquitin-protein ligase RNF128 antibody, FLJ23516 antibody, Gene related to anergy in lymphocytes protein antibody, GRAIL antibody, RING finger protein 128 antibody, RN128_HUMAN antibody, RNF128 antibody

    UniProt
    Q8TEB7
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