SMURF1 anticorps (AA 198-374) (Biotin)

N° du produit ABIN7151223

Détail du produit anti-SMURF1 anticorps (Biotin)

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Épitope: AA 198-374

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMURF1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase SMURF1 protein (198-374AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SMURF1

Antigène: SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

Autre désignation: SMURF1 (SMURF1 Produits)

Synonymes: anticorps 4930431E10Rik, anticorps mKIAA1625, anticorps RGD1309707, anticorps SMAD specific E3 ubiquitin protein ligase 1, anticorps E3 ubiquitin-protein ligase SMURF1, anticorps SMAD specific E3 ubiquitin protein ligase 1 L homeolog, anticorps SMURF1, anticorps LOC100540915, anticorps smurf1, anticorps Smurf1, anticorps smurf1.L

Sujet:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of BMP signaling pathway. Mediates ubiquitination and degradation of SMAD1 and SMAD5, 2 receptor-regulated SMADs specific for the BMP pathway. Promotes ubiquitination and subsequent proteasomal degradation of TRAF family members and RHOA. Plays a role in dendrite formation by melanocytes (PubMed:23999003).

Aliases: E3 ubiquitin-protein ligase SMURF1 antibody, hSMURF1 antibody, KIAA1625 antibody, Smad specific E3 ubiquitin ligase 1 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, Smad ubiquitination regulatory factor 1 antibody, SMAD-specific E3 ubiquitin-protein ligase 1 antibody, SMUF1_HUMAN antibody, SMURF 1 antibody, smurf1 antibody

UniProt: Q9HCE7

Pathways: Regulation of Cell Size