ZNRF3 anticorps (AA 56-219) (Biotin)

N° du produit ABIN7151319

Détail du produit anti-ZNRF3 anticorps (Biotin)

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Épitope: AA 56-219

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZNRF3 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human E3 ubiquitin-protein ligase ZNRF3 protein (56-219AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ZNRF3

Antigène: ZNRF3 (Zinc and Ring Finger Protein 3 (ZNRF3))

Autre désignation: ZNRF3 (ZNRF3 Produits)

Synonymes: anticorps BK747E2.3, anticorps RNF203, anticorps AA591877, anticorps BC019575, anticorps Gm1167, anticorps zinc and ring finger 3, anticorps Znrf3, anticorps ZNRF3

Sujet:

Background: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone.

Aliases: ZNRF3 antibody, KIAA1133 antibody, RNF203 antibody, E3 ubiquitin-protein ligase ZNRF3 antibody, EC 2.3.2.27 antibody, RING finger protein 203 antibody, RING-type E3 ubiquitin transferase ZNRF3 antibody, Zinc/RING finger protein 3 antibody

UniProt: Q9ULT6

Pathways: Signalisation WNT