Nth Endonuclease III-Like 1 (NTHL1) (AA 31-312) anticorps (HRP)

N° du produit ABIN7151638

Détail du produit

Antigène: Nth Endonuclease III-Like 1 (NTHL1)

Épitope: AA 31-312

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Endonuclease III-like protein 1 protein (31-312AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détail du antigène

Antigène: Nth Endonuclease III-Like 1 (NTHL1)

Autre désignation: NTHL1 (NTHL1 Produits)

Synonymes: anticorps psmc3, anticorps psmc3-a, anticorps nth-like DNA glycosylase 1 S homeolog, anticorps nthl1.S

Sujet:

Background: Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3\' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Acts preferentially on DNA damage opposite guanine residues in DNA. Is able to process lesions in nucleosomes without requiring or inducing nucleosome disruption.

Aliases: Bifunctional DNA N glycoslyase/DNA (apurinic or apyrimidinic site) lyase antibody, DNA glycoslyase/AP lyase antibody, Endonuclease III like protein 1 antibody, Endonuclease III-like protein 1 antibody, hNTH1 antibody, NTH 1 antibody, nth endonuclease III like 1 (E. coli) antibody, NTH endonuclease III Like 1 antibody, NTH1 antibody, NTHL 1 antibody, Nthl1 antibody, NTHL1_HUMAN antibody, OCTS 3 antibody, OCTS3 antibody

UniProt: P78549