SH3GLB1 anticorps (AA 1-365) (HRP)

N° du produit ABIN7151648

Détail du produit anti-SH3GLB1 anticorps (HRP)

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Épitope: AA 1-365

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SH3GLB1 est conjugé à/à la HRP

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Endophilin-B1 protein (1-365AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur SH3GLB1

Antigène: SH3GLB1 (SH3-Domain GRB2-Like Endophilin B1 (SH3GLB1))

Autre désignation: SH3GLB1 (SH3GLB1 Produits)

Synonymes: anticorps im:5777505, anticorps wu:fa08f03, anticorps wu:fb13e12, anticorps MGC79086, anticorps sh3glb1, anticorps wu:fc55h11, anticorps wu:fj98d09, anticorps AA409932, anticorps AI314629, anticorps AU015566, anticorps Bif-1, anticorps mKIAA0491, anticorps PPP1R70, anticorps dJ612B15.2, anticorps SH3-domain GRB2-like endophilin B1b, anticorps SH3 domain GRB2 like, endophilin B1 S homeolog, anticorps SH3 domain GRB2 like, endophilin B1, anticorps SH3 domain containing GRB2 like, endophilin B1, anticorps SH3-domain GRB2-like endophilin B1a, anticorps SH3-domain GRB2-like B1 (endophilin), anticorps SH3 domain -containing GRB2-like endophilin B1, anticorps SH3 domain containing GRB2 like endophilin B1, anticorps sh3glb1b, anticorps sh3glb1.S, anticorps sh3glb1, anticorps SH3GLB1, anticorps sh3glb1a, anticorps Sh3glb1

Sujet:

Background: May be required for normal outer mitochondrial membrane dynamics (PubMed:15452144). Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion (PubMed:11604418). Involved in activation of caspase-dependent apoptosis by promoting BAX/BAK1 activation (PubMed:16227588). Isoform 1 acts proapoptotic in fibroblasts. Involved in caspase-independent apoptosis during nutrition starvation and involved in the regulation of autophagy. Activates lipid kinase activity of PIK3C3 during autophagy probably by associating with the PI3K complex II (PI3KC3-C2) (PubMed:17891140). Associated with PI3KC3-C2 during autophagy may regulate the trafficking of ATG9A from the Golgi complex to the peripheral cytoplasm for the formation of autophagosomes by inducing Golgi membrane tubulation and fragmentation (PubMed:21068542). Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). Isoform 2 acts antiapoptotic in neuronal cells, involved in maintenance of mitochondrial morphology and promotes neuronal viability.

Aliases: Bax interacting factor 1 antibody, Bax-interacting factor 1 antibody, Bif 1 antibody, Bif antibody, Bif-1 antibody, CGI 61 antibody, dJ612B15.2 antibody, Endophilin B1 antibody, Endophilin-B1 antibody, PPP1R70 antibody, Protein phosphatase 1 regulatory subunit 70 antibody, SH3 containing protein SH3GLB1 antibody, SH3 domain GRB2 like endophilin B1 antibody, SH3 domain-containing GRB2-like protein B1 antibody, Sh3glb1 antibody, SH3p13 antibody, SHLB1_HUMAN antibody

UniProt: Q9Y371

Pathways: Autophagy