ERAP1 anticorps (AA 642-941) (Biotin)

N° du produit ABIN7151656

Détail du produit anti-ERAP1 anticorps (Biotin)

Antigène: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Épitope: AA 642-941

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERAP1 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Endoplasmic reticulum aminopeptidase 1 protein (642-941AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERAP1

Antigène: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Autre désignation: ERAP1 (ERAP1 Produits)

Synonymes: anticorps MGC166160, anticorps DKFZp469C044, anticorps ARTS-1, anticorps A-LAP, anticorps ALAP, anticorps APPILS, anticorps ARTS1, anticorps ERAAP, anticorps ERAAP1, anticorps PILS-AP, anticorps PILSAP, anticorps Arts1, anticorps PILSA, anticorps Appils, anticorps endoplasmic reticulum aminopeptidase 1, anticorps endoplasmic reticulum aminopeptidase 1b, anticorps ERAP1, anticorps erap1, anticorps erap1b, anticorps Erap1

Sujet:

Background: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney.

Aliases: A LAP antibody, A-LAP antibody, Adipocyte derived leucine aminopeptidase antibody, Adipocyte-derived leucine aminopeptidase antibody, ALAP antibody, Aminopeptidase PILS antibody, Aminopeptidase regulator of TNFR1 shedding antibody, APPILS antibody, ARTS 1 antibody, ARTS-1 antibody, Arts1 antibody, Endoplasmic reticulum aminopeptidase 1 antibody, Endoplasmic reticulum aminopeptidase associated with antigen processing antibody, ERAAP antibody, ERAAP1 antibody, ERAP 1 antibody, Erap1 antibody, ERAP1_HUMAN antibody, KIAA0525 antibody, kiaa0525 protein antibody, PILS AP antibody, PILS-AP antibody, PILSA antibody, PILSAP antibody, Puromycin insensitive leucyl specific aminopeptidase antibody, Puromycin-insensitive leucyl-specific aminopeptidase antibody, Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody, type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody, VEGF-induced aminopeptidase antibody

UniProt: Q9NZ08