ERP29 anticorps (AA 40-251)

N° du produit ABIN7151681

Détail du produit anti-ERP29 anticorps

Antigène: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Épitope: AA 40-251

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERP29 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Endoplasmic reticulum resident protein 29 protein (40-251AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERP29

Antigène: ERP29 (Endoplasmic Reticulum Protein 29 (ERP29))

Autre désignation: ERP29 (ERP29 Produits)

Synonymes: anticorps C12orf8, anticorps ERp28, anticorps ERp31, anticorps PDI-DB, anticorps PDIA9, anticorps 1200015M03Rik, anticorps 2810446M09Rik, anticorps AW209030, anticorps Erp28, anticorps Erp31, anticorps PDI-Db, anticorps endoplasmic reticulum protein 29, anticorps ERP29, anticorps Erp29

Sujet:

Background: Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticulum. This task is accomplished by chaperone proteins such as protein disulfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregulated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticulum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI's thioredoxin module. The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER.

Aliases: ERP29 antibody, C12orf8 antibody, ERP28Endoplasmic reticulum resident protein 29 antibody, ERp29 antibody, Endoplasmic reticulum resident protein 28 antibody, ERp28 antibody, Endoplasmic reticulum resident protein 31 antibody, ERp31 antibody

UniProt: P30040