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NGEF anticorps (AA 495-710) (HRP)

NGEF Reactivité: Humain ELISA Hôte: Lapin Polyclonal HRP
N° du produit ABIN7151826
  • Antigène Voir toutes NGEF Anticorps
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Épitope
    • 15
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 495-710
    Reactivité
    • 41
    • 41
    • 33
    • 3
    • 3
    • 3
    • 3
    Humain
    Hôte
    • 47
    • 1
    Lapin
    Clonalité
    • 47
    • 1
    Polyclonal
    Conjugué
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp NGEF est conjugé à/à la HRP
    Application
    • 39
    • 26
    • 26
    • 10
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    ELISA
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Ephexin-1 protein (495-710AA)
    Isotype
    IgG
    Top Product
    Discover our top product NGEF Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
    Autre désignation
    NGEF (NGEF Produits)
    Synonymes
    anticorps Ephexin-1, anticorps ARHGEF27, anticorps EPHEXIN, anticorps Tims2, anticorps ephexin, anticorps Besh3, anticorps ephexin-1, anticorps neuronal guanine nucleotide exchange factor, anticorps NGEF, anticorps Ngef
    Sujet

    Background: Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).

    Aliases: ARHGEF27 antibody, Eph receptor-interacting exchange protein antibody, Eph-interacting exchange protein antibody, EPHEXIN antibody, Ephexin-1 antibody, Guanine nucleotide exchange factor, neuronal antibody, Neuronal guanine nucleotide exchange factor antibody, Ngef antibody, NGEF_HUMAN antibody

    UniProt
    Q8N5V2
    Pathways
    Neurotrophin Signaling Pathway
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