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Ephrin A1 anticorps (AA 19-182)

EFNA1 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7151874
  • Antigène Voir toutes Ephrin A1 (EFNA1) Anticorps
    Ephrin A1 (EFNA1)
    Épitope
    • 15
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 19-182
    Reactivité
    • 40
    • 22
    • 18
    • 1
    Humain
    Hôte
    • 45
    • 2
    • 1
    • 1
    Lapin
    Clonalité
    • 45
    • 4
    Polyclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Ephrin A1 est non-conjugé
    Application
    • 22
    • 18
    • 13
    • 13
    • 11
    • 7
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    Antigen Affinity Purified
    Immunogène
    Recombinant Human Ephrin-A1 protein (19-182AA)
    Isotype
    IgG
    Top Product
    Discover our top product EFNA1 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    Ephrin A1 (EFNA1)
    Autre désignation
    EFNA1 (EFNA1 Produits)
    Synonymes
    anticorps Xefrin-A1, anticorps b61, anticorps ecklg, anticorps efl1, anticorps efna1, anticorps efna1a, anticorps elfa-a, anticorps epha1, anticorps eplg1, anticorps lerk1, anticorps tnfaip4, anticorps xelf-a', anticorps xelfa, anticorps AI325262, anticorps B61, anticorps Efl1, anticorps Epl1, anticorps Eplg1, anticorps Lerk1, anticorps ECKLG, anticorps EFL1, anticorps EPLG1, anticorps LERK-1, anticorps LERK1, anticorps TNFAIP4, anticorps efna1b, anticorps MGC130661, anticorps ephrin-A1 S homeolog, anticorps ephrin-A1, anticorps ephrin A1, anticorps ephrin-A1b, anticorps ephrin-A1 L homeolog, anticorps efna1.S, anticorps efna1, anticorps EFNA1, anticorps efna1b, anticorps Efna1, anticorps efna1.L
    Sujet

    Background: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. Plays an important role in angiogenesis and tumor neovascularization. The recruitment of VAV2, VAV3 and PI3-kinase p85 subunit by phosphorylated EPHA2 is critical for EFNA1-induced RAC1 GTPase activation and vascular endothelial cell migration and assembly. Exerts anti-oncogenic effects in tumor cells through activation and down-regulation of EPHA2. Activates EPHA2 by inducing tyrosine phosphorylation which leads to its internalization and degradation. Acts as a negative regulator in the tumorigenesis of gliomas by down-regulating EPHA2 and FAK. Can evoke collapse of embryonic neuronal growth cone and regulates dendritic spine morphogenesis.

    Aliases: B61 antibody, ECKLG antibody, EFL 1 antibody, EFL1 antibody, EFNA 1 antibody, Efna1 antibody, EFNA1_HUMAN antibody, EPH related receptor tyrosine kinase ligand 1 antibody, EPH-related receptor tyrosine kinase ligand 1 antibody, Ephrin-A1 antibody, Ephrin-A1, secreted form antibody, EphrinA1 antibody, EPLG 1 antibody, EPLG1 antibody, Immediate early response protein B61 antibody, LERK 1 antibody, LERK-1 antibody, LERK1 antibody, Ligand of eph related kinase 1 antibody, OTTHUMP00000033242 antibody, OTTHUMP00000033271 antibody, secreted form antibody, TNF alpha-induced protein 4 antibody, TNFAIP 4 antibody, TNFAIP4 antibody, Tumor necrosis factor alpha induced protein 4 antibody, Tumor necrosis factor alpha-induced protein 4 antibody

    UniProt
    P20827
    Pathways
    Signalisation RTK
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