EDEM1 anticorps (AA 46-128)

N° du produit ABIN7151970

Détail du produit anti-EDEM1 anticorps

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Épitope: AA 46-128

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EDEM1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: IHC:1:200-1:500,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur EDEM1

Antigène: EDEM1 (ER Degradation Enhancer, Mannosidase alpha-Like 1 (EDEM1))

Autre désignation: EDEM1 (EDEM1 Produits)

Synonymes: anticorps zgc:55816, anticorps edem, anticorps EDEM1, anticorps EDEM, anticorps A130059K23Rik, anticorps mKIAA0212, anticorps RGD1563633, anticorps ER degradation enhancer, mannosidase alpha-like 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1, anticorps ER degradation-enhancing alpha-mannosidase-like protein 1, anticorps ER degradation enhancing alpha-mannosidase like protein 1 L homeolog, anticorps edem1, anticorps EDEM1, anticorps LOC100637820, anticorps edem1.L, anticorps Edem1

Sujet:

Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.

Aliases: EDEM1 antibody, EDEM antibody, KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody

UniProt: Q92611

Pathways: ER-Nucleus Signaling