ERLIN2 anticorps (AA 25-206) (Biotin)

N° du produit ABIN7151999

Détail du produit anti-ERLIN2 anticorps (Biotin)

Antigène: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Épitope: AA 25-206

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERLIN2 est conjugé à/à la Biotin

Application: ELISA

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human Erlin-2 protein (25-206AA)

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERLIN2

Antigène: ERLIN2 (ER Lipid Raft Associated 2 (ERLIN2))

Autre désignation: ERLIN2 (ERLIN2 Produits)

Synonymes: anticorps C8orf2, anticorps Erlin-2, anticorps NET32, anticorps SPFH2, anticorps SPG18, anticorps BC036333, anticorps C87251, anticorps Spfh2, anticorps Erlin-2-B, anticorps erlin1, anticorps spfh1, anticorps spfh2, anticorps spfh2-B, anticorps RGD1309010, anticorps SPFH domain-containing protein 2-A, anticorps erlin2, anticorps erlin2-a, anticorps erlin2-b, anticorps spfh2-A, anticorps ER lipid raft associated 2, anticorps erlin-2, anticorps Erlin-2, anticorps ER lipid raft associated 2 S homeolog, anticorps ER lipid raft associated 2 L homeolog, anticorps ERLIN2, anticorps erlin2, anticorps Tsp_03442, anticorps erln2, anticorps Erlin2, anticorps erlin2.S, anticorps erlin2.L

Sujet:

Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation (ERAD) of inositol 1,4,5-trisphosphate receptors (IP3Rs) such as ITPR1 (PubMed:19240031, PubMed:17502376). Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. May promote ER retention of the SCAP-SREBF complex (PubMed:24217618).

Aliases: C8orf2 antibody, Chromosome 8 open reading frame 2 antibody, Endoplasmic reticulum lipid raft associated protein 2 antibody, Endoplasmic reticulum lipid raft-associated protein 2 antibody, ER lipid raft associated 2 antibody, ERLIN 2 antibody, Erlin-2 antibody, ERLIN2 antibody, ERLN2_HUMAN antibody, HGNC:1356 antibody, MGC87072 antibody, NET32 antibody, SPFH 2 antibody, SPFH domain containing protein 2 antibody, SPFH domain family member 2 antibody, SPFH domain-containing protein 2 antibody, SPFH2 antibody, SPG18 antibody, Stomatin prohibitin flotillin HflC/K domain containing protein 2 antibody, Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2 antibody

UniProt: O94905