ERO1LB anticorps (AA 101-400)

N° du produit ABIN7152004

Détail du produit anti-ERO1LB anticorps

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Épitope: AA 101-400

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERO1LB est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Réactivité croisée: Humain, Souris

Purification: >95%, Protein G purified

Immunogène: Recombinant Human ERO1-like protein beta protein (101-400AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur ERO1LB

Antigène: ERO1LB (ERO1-Like beta (ERO1LB))

Autre désignation: ERO1B (ERO1LB Produits)

Synonymes: anticorps RGD1563548, anticorps 1300013B24Rik, anticorps 1700065B09Rik, anticorps AI447560, anticorps ero1-beta, anticorps endoplasmic reticulum oxidoreductase 1 beta, anticorps ERO1-like beta (S. cerevisiae), anticorps Ero1b, anticorps ERO1B, anticorps Ero1lb

Sujet:

Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

Aliases: Endoplasmic oxidoreductin-1-like protein B antibody, Endoplasmic reticulum oxidoreductin-1-like protein B antibody, ERO1, S. cerevisiae, homolog of, beta antibody, ERO1-L-beta antibody, ERO1-like beta (S. cerevisiae) antibody, ERO1-like protein beta antibody, ERO1B_HUMAN antibody, Ero1lb antibody, Oxidoreductin-1-L-beta antibody

UniProt: Q86YB8

Pathways: SARS-CoV-2 Protein Interactome