EIF3A anticorps (AA 1288-1379) (Biotin)
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- Antigène Voir toutes EIF3A Anticorps
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
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Épitope
- AA 1288-1379
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp EIF3A est conjugé à/à la Biotin
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Application
- ELISA
- Réactivité croisée
- Humain
- Purification
- >95%, Protein G purified
- Immunogène
- Recombinant Human Eukaryotic translation initiation factor 3 subunit A protein (1288-1379AA)
- Isotype
- IgG
- Top Product
- Discover our top product EIF3A Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Antigène
- EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))
- Autre désignation
- EIF3A (EIF3A Produits)
- Synonymes
- anticorps EIF3, anticorps EIF3S10, anticorps P167, anticorps TIF32, anticorps eIF3-p170, anticorps eIF3-theta, anticorps p180, anticorps p185, anticorps EIF6, anticorps A830012B05Rik, anticorps Csma, anticorps Eif3, anticorps Eif3s10, anticorps mKIAA0139, anticorps ZH12, anticorps eif3s10, anticorps eIF3 p110, anticorps eIF3a, anticorps eukaryotic translation initiation factor 3 subunit A, anticorps eukaryotic translation initiation factor 3, subunit A, anticorps eukaryotic translation initiation factor 3 subunit A S homeolog, anticorps translation initiation factor eIF3a, anticorps EIF3A, anticorps Eif3a, anticorps eif3a.S, anticorps tif32
- Sujet
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Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. Essential for the initiation of translation on type-1 viral ribosomal entry sites (IRESs), like for HCV, PV, EV71 or BEV translation (PubMed:23766293, PubMed:24357634). In case of FCV infection, plays a role in the ribosomal termination-reinitiation event leading to the translation of VP2 (PubMed:18056426).
Aliases: centrosomin homolog antibody, cytoplasmic protein p167 antibody, eIF 3 theta antibody, eIF-3-theta antibody, EIF3 antibody, eIF3 p167 antibody, eIF3 p170 antibody, eIF3 p180 antibody, EIF3 p180 subunit antibody, eIF3 p185 antibody, eIF3 theta antibody, eIF3a antibody, EIF3A_HUMAN antibody, EIF3S10 antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 150 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 (theta 170kD) antibody, eukaryotic translation initiation factor 3 subunit 10 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit 10 antibody, eukaryotic translation initiation factor 3 subunit 10 theta 150 170 kDa antibody, Eukaryotic translation initiation factor 3 subunit A antibody, OTTHUMP00000020589 antibody, P167 antibody, p180 antibody, p185 antibody, TIF32 antibody
- UniProt
- Q14152
- Pathways
- Ribonucleoprotein Complex Subunit Organization
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