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EXOSC5 anticorps (AA 1-235) (FITC)

EXOSC5 Reactivité: Humain Hôte: Lapin Polyclonal FITC
N° du produit ABIN7152295
  • Antigène Voir toutes EXOSC5 Anticorps
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Épitope
    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    AA 1-235
    Reactivité
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 26
    • 5
    Lapin
    Clonalité
    • 28
    • 3
    Polyclonal
    Conjugué
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EXOSC5 est conjugé à/à la FITC
    Application
    Veuillez nous consulter SVP
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Exosome complex component RRP46 protein (1-235AA)
    Isotype
    IgG
    Top Product
    Discover our top product EXOSC5 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    EXOSC5 (Exosome Component 5 (EXOSC5))
    Autre désignation
    EXOSC5 (EXOSC5 Produits)
    Synonymes
    anticorps si:ch211-194n6.2, anticorps zgc:153707, anticorps EXOSC5, anticorps RRP41B, anticorps RRP46, anticorps Rrp46p, anticorps hRrp46p, anticorps p12B, anticorps D7Wsu180e, anticorps exosome component 5, anticorps exosc5, anticorps EXOSC5, anticorps Exosc5
    Sujet

    Background: Non-catalytic component of the RNA exosome complex which has 3\'->5\' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding \'pervasive\' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3\' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. The catalytic inactive RNA exosome core complex of 9 subunits (Exo-9) is proposed to play a pivotal role in the binding and presentation of RNA for ribonucleolysis, and to serve as a scaffold for the association with catalytic subunits and accessory proteins or complexes.

    Aliases: Chronic myelogenous leukemia tumor antigen 28 antibody, CML28 antibody, EXOS5_HUMAN antibody, EXOSC 5 antibody, Exosc5 antibody, Exosome complex component rrp46 antibody, exosome complex exonuclease RRP46 antibody, Exosome component 5 antibody, exosome component Rrp46 antibody, hRrp46p antibody, p12B antibody, Ribosomal RNA processing protein 46 antibody, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of antibody, Ribosomal RNA-processing protein 46 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody

    UniProt
    Q9NQT4
    Pathways
    SARS-CoV-2 Protein Interactome
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