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EYA2 anticorps (AA 1-514)

EYA2 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7152359
  • Antigène Voir toutes EYA2 Anticorps
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Épitope
    • 15
    • 7
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-514
    Reactivité
    • 41
    • 19
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 53
    • 3
    Lapin
    Clonalité
    • 54
    • 2
    Polyclonal
    Conjugué
    • 20
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp EYA2 est non-conjugé
    Application
    • 44
    • 25
    • 13
    • 13
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    ELISA, Immunohistochemistry (IHC)
     Réactivité croisée
    Humain
    Purification
    >95%, Protein G purified
    Immunogène
    Recombinant Human Eyes absent homolog 2 protein (1-514AA)
    Isotype
    IgG
    Top Product
    Discover our top product EYA2 Anticorps primaire
  • Indications d'application
    Recommended dilution: IHC:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Antigène
    EYA2 (Eyes Absent Homolog 2 (Drosophila) (EYA2))
    Autre désignation
    EYA2 (EYA2 Produits)
    Synonymes
    anticorps EYA2, anticorps zgc:92279, anticorps eab1, anticorps Eab1, anticorps EAB1, anticorps EYA transcriptional coactivator and phosphatase 2, anticorps EYA2, anticorps eya2, anticorps Eya2
    Sujet

    Background: Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5. Tyrosine phosphatase that dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Its function as histone phosphatase may contribute to its function in transcription regulation during organogenesis. Plays an important role in hypaxial muscle development together with SIX1 and DACH2, in this it is functionally redundant with EYA1.

    Aliases: EAB 1 antibody, EAB1 antibody, EYA 2 antibody, EYA transcriptional coactivator and phosphatase 2 antibody, EYA2 antibody, EYA2_HUMAN antibody, eyes absent 2 homolog (Drosophila) antibody, Eyes absent homolog 2 (Drosophila) antibody, Eyes absent homolog 2 antibody, Translation of this uORF probably lowers the translation efficiency of EYA2 antibody

    UniProt
    O00167
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